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The use of Brilliant Blue FCF in tetracycline intramammary preparations

Authors: J.T. Feagan and A.T. Griffin


Oxytetracycline HCl intramammary preparations in a water miscible base could be satisfactorily dyed with Brilliant Blue F.C.F. When dyed at the rate of 0.25 gm dye per 426 mg oxytetracycline HCl, the dye and the antibiotic disappeared from the milk of treated cows at the same rate. Exclusion of dyed milk excluded 99.9% of the antibiotic. The dye did not affect the stability of the antibiotic.

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